The influence of aluminium, administered in the diet and in drinking water, on biopterin metabolism

Armstrong, Richard A.; Anderson, J.; Cowburn, Jim D.; Cox, Juliette and Blair, J.A. The influence of aluminium, administered in the diet and in drinking water, on biopterin metabolism. IN: 11th Winter Workshop on Pteridines. 1992-02-15 - 1992-02-22. (Unpublished)

Abstract

To investigate the neurotoxic effects of aluminium (Al) three studies were carried out in which Al was administered: 1) in the diet, 2) as a suspension of aluminium acetate in drinking water and 3) a long-term study in which aluminosilicates were incorporated into a pelleted diet. Admistration of Al in the drinking water significantly reduced total brain biopterin. However, no significant affect of Al in the diet on total bipterins or BH4 synthesis was found.

Divisions: Life & Health Sciences > Optometry
Life & Health Sciences > Ophthalmic Research Group
Life & Health Sciences > Health Sciences
Additional Information: Abstract appearing in Biol Chem, 373:P986
Event Title: 11th Winter Workshop on Pteridines
Event Type: Other
Event Dates: 1992-02-15 - 1992-02-22
Uncontrolled Keywords: neurotoxic effects,aluminium,brain

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