Accuracy of cornea and lens biometry using anterior segment optical coherence tomography

Dunne, Mark C.M., Davies, Leon N. and Wolffsohn, James S.W. (2007). Accuracy of cornea and lens biometry using anterior segment optical coherence tomography. Journal of Biomedical Optics, 12 (6), 064023.

Abstract

We assess the accuracy of the Visante anterior segment optical coherence tomographer (AS-OCT) and present improved formulas for measurement of surface curvature and axial separation. Measurements are made in physical model eyes. Accuracy is compared for measurements of corneal thickness (d1) and anterior chamber depth (d2) using-built-in AS-OCT software versus the improved scheme. The improved scheme enables measurements of lens thickness (d 3) and surface curvature, in the form of conic sections specified by vertex radii and conic constants. These parameters are converted to surface coordinates for error analysis. The built-in AS-OCT software typically overestimates (mean±standard deviation(SD)]d1 by +62±4 μm and d2 by +4±88μm. The improved scheme reduces d1 (-0.4±4 μm) and d2 (0±49 μm) errors while also reducing d3 errors from +218±90 (uncorrected) to +14±123 μm (corrected). Surface x coordinate errors gradually increase toward the periphery. Considering the central 6-mm zone of each surface, the x coordinate errors for anterior and posterior corneal surfaces reached +3±10 and 0±23 μm, respectively, with the improved scheme. Those of the anterior and posterior lens surfaces reached +2±22 and +11±71 μm, respectively. Our improved scheme reduced AS-OCT errors and could, therefore, enhance pre- and postoperative assessments of keratorefractive or cataract surgery, including measurement of accommodating intraocular lenses. © 2007 Society of Photo-Optical Instrumentation Engineers.

Publication DOI: https://doi.org/10.1117/1.2821844
Divisions: Life & Health Sciences > Optometry
Life & Health Sciences > Ophthalmic Research Group
Life & Health Sciences
Additional Information: Copyright 2007 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Uncontrolled Keywords: accuracy,anterior segment optical coherence tomography,biometry,physical model eyes,Biomedical Engineering,Biomaterials,Electronic, Optical and Magnetic Materials,Atomic and Molecular Physics, and Optics,Radiology Nuclear Medicine and imaging,Radiological and Ultrasound Technology,Clinical Biochemistry
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Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
https://www.spi ... 1844.full?SSO=1 (Publisher URL)
Published Date: 2007-12-18
Authors: Dunne, Mark C.M. ( 0000-0001-9126-0702)
Davies, Leon N. ( 0000-0002-1554-0566)
Wolffsohn, James S.W. ( 0000-0003-4673-8927)

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