Organic reactions in ionic liquids:An efficient method for selective S-alkylation of 2-mercaptobenzothia(xa)zole with alkyl halides

Hu, Yi, Chen, Zhen-Chu, Le, Zhang-Gao and Zheng, Qinguo (2004). Organic reactions in ionic liquids:An efficient method for selective S-alkylation of 2-mercaptobenzothia(xa)zole with alkyl halides. Synthetic communications, 34 (11), pp. 2039-2046.

Abstract

Ionic liquids based on 1-butyl-3-methylimidazolium hexafluorophosphate (BmimPF6) and 1-butyl-3-methylimidazolium tetrafluoroborate (BmimBF4) are used as reusable reaction medium in the selective S-alkylation of 2-mercaptobenzothia(xa)zole with alkyl halides in the presence of potassium carbonate. This procedure is convenient, efficient, and generally gives rise to the S-alkylated product exclusively.

Publication DOI: https://doi.org/10.1081/SCC-120037917
Divisions: Life & Health Sciences > Pharmacy
Life & Health Sciences
Uncontrolled Keywords: 2-Mercaptobenzothia(xa)zole,alkyl halides,ionic liquids,organic reaction,S-Alkylation,Organic Chemistry
Full Text Link: http://www.info ... e=11&spage=2039
Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
Published Date: 2004-06-28
Authors: Hu, Yi
Chen, Zhen-Chu
Le, Zhang-Gao
Zheng, Qinguo

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