SPIV and image correlation measurements of surface displacement during pulsatile flow in models of compliant, healthy and stenosed arteries

Geoghegan, Patrick H, Buchmann, N, Jermy, Mark C., Nobes, David, Spence, C. J.T. and Docherty, Paul D (2010). SPIV and image correlation measurements of surface displacement during pulsatile flow in models of compliant, healthy and stenosed arteries. IN: 15th international symposium of laser techniques to fluid mechanics. 2010-07-05 - 2010-07-08.

Abstract

Compliant structures are important in several biofluid flow problems including the heart, lungs and abdominal aortic aneurysms where the walls move under the influence of the fluid pressure and muscle action. Coronary heart disease (CHD) is a major cause of death in the U.S.A with approximately 650,000 fatalities a year and involves a progressive constriction of the coronary artery by atherosclerosis. Blood flow is reduced and when under stress the heart muscle is deprived of oxygen and nutrients. The blood flow in the coronary artery is strongly influenced by the flexing of the artery wall. In this work a method for manufacturing silicone models with compliance controlled by the wall thickness and the cross-wall (transmural) pressure difference, of arteries with varying stenosis (narrowing related to atherosclerosis and other circulatory diseases), is demonstrated. PIV analysis is used to compare results between a rigid and compliant straight tube model experiencing a physiological realistic flow wave with in vivo parameters of time period 1s, mean and peak Reynolds numbers 540 and 920 respectively and a Womersley number of 4.54. In vitro results are obtained in models scaled to 2.8 times in vivo dimensions. A method for analysing 3 dimensional surface displacement is used to study the effects of static loading on compliant models with 30% symmetric and asymmetric stenosis. The results show that at physiologically relevant levels of compliance there is a variation in the flow field when compared to rigid pipes and that the surface displacement is dominated by radial motion with a smaller axial motion being present.

Divisions: Life & Health Sciences
Event Title: 15th international symposium of laser techniques to fluid mechanics
Event Type: Other
Event Dates: 2010-07-05 - 2010-07-08
Full Text Link: http://ltces.de ... 3.Full_1595.pdf
Related URLs:
Published Date: 2010
Authors: Geoghegan, Patrick H ( 0000-0003-1224-0477)
Buchmann, N
Jermy, Mark C.
Nobes, David
Spence, C. J.T.
Docherty, Paul D

Export / Share Citation


Statistics

Additional statistics for this record