Modeling anthropometric indices in relation to 10-year (2002-2012) incidence of cardiovascular disease, among apparently healthy individuals:the ATTICA study

Filippatos, Theodosios D., Kyrou, Ioannis, Georgousopoulou, Ekavi N., Chrysohoou, Christina, Kouli, Georgia-Maria, Tsigos, Constantine, Tousoulis, Dimitrios, Stefanadis, Christodoulos, Pitsavos, Christos and Panagiotakos, Demosthenes B. (2017). Modeling anthropometric indices in relation to 10-year (2002-2012) incidence of cardiovascular disease, among apparently healthy individuals:the ATTICA study. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, in pre ,

Abstract

Aims: Body fat accumulation is implicated in the development of cardiovascular disease (CVD). Our objective was to explore potential associations between anthropometric indices and the 10-year CVD incidence in Greek adults without previous CVD. Methods: During 2001–2, we enrolled 3042 adults without CVD from the general population of Attica, Greece. In 2011–2, the 10-year study follow-up was performed, recording the CVD incidence in 1958 participants with baseline body mass index (BMI) ≥18.5 kg/m2. Results: The study 10-year CVD incidence was 15.8%, exhibiting a gradual increase according to the baseline body mass index (BMI) category. Baseline BMI ≥30 kg/m2 was related with significantly higher 10-year CVD risk compared to BMI <25 kg/m2, even after adjustment for age and other known CVD risk factors. Baseline BMI, waist circumference, waist-to-hip ratio, waist-to-height ratio and waist-to-hip-to-height ratio were independently associated with the 10-year CVD risk in multi-adjusted models. Gender-specific analyses showed that these associations were more evident in men compared to women, with baseline BMI exhibiting an independent association with the 10-year CVD incidence in men. Conclusions: Our results indicate that even simple anthropometric indices exhibit independent associations with CVD risk in a representative sample of the Greek general population without previous CVD.

Publication DOI: https://doi.org/10.1016/j.dsx.2017.05.018
Divisions: Aston Medical School
Additional Information: © 2017, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/
Uncontrolled Keywords: anthropometric indices,cardiovascular disease,body mass index,waist circumference,obesity,Internal Medicine,Endocrinology, Diabetes and Metabolism
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Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
Published Online Date: 2017-06-03
Authors: Filippatos, Theodosios D.
Kyrou, Ioannis ( 0000-0002-6997-3439)
Georgousopoulou, Ekavi N.
Chrysohoou, Christina
Kouli, Georgia-Maria
Tsigos, Constantine
Tousoulis, Dimitrios
Stefanadis, Christodoulos
Pitsavos, Christos
Panagiotakos, Demosthenes B.

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