The blood perfusion and NADH/FAD content combined analysis in patients with diabetes foot

Dremin, Victor V., Sidorov, Victor V., Krupatkin, Alexander I., Galstyan, Gagik R., Novikova, Irina N., Zherebtsova, Angelina I., Zherebtsov, Evgeny A., Dunaev, Andrey V., Abdulvapova, Zera N., Litvinova, Karina S., Rafailov, Ilya E., Sokolovski, Sergei G. and Rafailov, Edik U. (2016). The blood perfusion and NADH/FAD content combined analysis in patients with diabetes foot. IN: Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV. Vo-Dinh, Tuan; Mahadevan-Jansen, Anita and Grundfest, Warren S. (eds) Progress in Biomedical Optics and Imaging . Bellingham, WA (US): SPIE.

Abstract

Skin blood microcirculation and the metabolism activity of tissue were examined on the patients with type 2 diabetes. Laser Doppler flowmetry (LDF) with 1064 nm laser light source and fluorescence spectroscopy (FS) with excitation light of 365 nm and 450 nm have been used to monitor the blood perfusion and the content of coenzymes NADH and FAD. Concluding, the proposed combined LDF and tissue FS approach allows to identify the significant violations in the blood microcirculation and metabolic activity for type 2 diabetes patients.

Publication DOI: https://doi.org/10.1117/12.2212758
Divisions: Engineering & Applied Sciences
Engineering & Applied Sciences > Electrical, electronic & power engineering
Engineering & Applied Sciences > Institute of Photonics
Additional Information: Victor V. Dremin; Victor V. Sidorov; Alexander I. Krupatkin; Gagik R. Galstyan; Irina N. Novikova; Angelina I. Zherebtsova; Evgeny A. Zherebtsov; Andrey V. Dunaev; Zera N. Abdulvapova; Karina S. Litvinova; Ilya E. Rafailov; Sergei G. Sokolovski and Edik U. Rafailov; "The blood perfusion and NADH/FAD content combined analysis in patients with diabetes foot", Proc. SPIE 9698, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV, 969810 (March 7, 2016). Copyright 2016. Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited. DOI: http://dx.doi.org/10.1117/12.2212758
Event Title: Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIV
Event Type: Other
Event Dates: 2016-02-14 - 2016-02-16
Uncontrolled Keywords: diabetic foot syndrome,fluorescence spectroscopy,laser Doppler flowmetry,microcirculation,redox ratio,Atomic and Molecular Physics, and Optics,Electronic, Optical and Magnetic Materials,Biomaterials,Radiology Nuclear Medicine and imaging
Full Text Link: http://proceedi ... ticleid=2501708
Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
Published Date: 2016-03-07
Authors: Dremin, Victor V.
Sidorov, Victor V.
Krupatkin, Alexander I.
Galstyan, Gagik R.
Novikova, Irina N.
Zherebtsova, Angelina I.
Zherebtsov, Evgeny A.
Dunaev, Andrey V.
Abdulvapova, Zera N.
Litvinova, Karina S.
Rafailov, Ilya E.
Sokolovski, Sergei G.
Rafailov, Edik U. ( 0000-0002-4152-0120)

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