Contrast sensitivity improves after brimonidine therapy in primary open angle glaucoma:a case for neuroprotection

Evans, D.W., Hosking, S.L., Gherghel, D. and Bartlett, J.D. (2003). Contrast sensitivity improves after brimonidine therapy in primary open angle glaucoma:a case for neuroprotection. British Journal of Ophthalmology, 87 (12), pp. 1463-1465.

Abstract

Aims: To determine the visual outcome following initiation of brimonidine therapy in glaucoma. Methods: 16 newly diagnosed previously untreated glaucoma patients were randomly assigned to either timalal 0.5% or brimanidine 0.2%. Visual acuity, contrast sensitivity (CS), visual fields, intraocular pressure (IOP), blaad pressure, and heart rate were evaluated at baseline and after 3 months. Results: IOP reduction was similar far both groups (p<0.05). Brimanidine improved CS; in the right eye at 6 and 12 cpd (p = 0.043, p = 0.017); in the left eye at 3 and 12 cpd (p = 0.044, p = 0.046). Timolol reduced CS at 18 cpd in the right eye (p = 0.041). There was no change in any other measured parameters. Conclusion: Glaucoma patients exhibit improved CS an initiation of brimanidine therapy.

Publication DOI: https://doi.org/10.1136/bjo.87.12.1463
Divisions: Life & Health Sciences > Optometry
Life & Health Sciences > Ophthalmic Research Group
Life & Health Sciences
Uncontrolled Keywords: Ophthalmology
Full Text Link: http://bjo.bmj. ... 2/1463.abstract
Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
Published Date: 2003-12
Authors: Evans, D.W.
Hosking, S.L.
Gherghel, D. ( 0000-0001-9439-5573)
Bartlett, J.D.

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