Innate immunity and apoptosis:CD14-dependent clearance of apoptotic cells

Gregory, Christopher D. and Devitt, Andrew (2003). Innate immunity and apoptosis:CD14-dependent clearance of apoptotic cells. IN: Apoptosis and autoimmunity. Hermann, M. and Kalden, J.R. (eds) Weinheim (DE): Wiley-VCH.

Abstract

This is the first comprehensive book about the relationship between apoptosis and autoimmune diseases. It offers a unique up–to–date overview on research results on the defective execution of apoptosis and the incomplete clearance of apoptotic cells. The molecular and cellular mechanisms involved are described in detail. As a possible consequence of apoptotic dysfunction, the development of severe autoimmune diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus) is discussed. An outlook on future research topics includes the evaluation of novel therapeutic strategies.

Divisions: Life & Health Sciences > Biosciences
Life & Health Sciences
Published Date: 2003-01-21
Authors: Gregory, Christopher D.
Devitt, Andrew ( 0000-0002-4651-6761)

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