Measurement of apoptotic cell clearance in vitro

Devitt, Andrew and Gregory, Christopher D. (2004). Measurement of apoptotic cell clearance in vitro. IN: Apoptosis methods and protocols. Brady, Hugh J.M. (ed.) Methods in molecular biology . Totowa, NL (US): Humana Press.


The phagocytic clearance of apoptotic cells is a highly efficient and nonphlogistic process in vivo. Research in this area has been limited, at least in part, by technical difficulties associated with the techniques used in the detailed study of apoptotic cell clearance mechanisms. This chapter provides details of methods that may be used to study apoptotic cell clearance in vitro. Such methods have been used successfully to identify phagocyte-associated or apoptotic cell-associated molecular players in the recognition process.

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Divisions: Life & Health Sciences
Life & Health Sciences > Applied Health Research Group
Life & Health Sciences > Biomedical Sciences research group
Life & Health Sciences > Biosciences
Uncontrolled Keywords: phagocytosis,apoptosis,B-lymphocytes,COS cells,cell line,cercopithecus aethiops,membrane proteins,macrophages
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Published Date: 2004
Authors: Devitt, Andrew ( 0000-0002-4651-6761)
Gregory, Christopher D.


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