Factors affecting corneoscleral topography

Hall, Lee, Hunt, Chris, Young, Graeme and Wolffsohn, James (2013). Factors affecting corneoscleral topography. Investigative Ophthalmology and Visual Science, 54 (5), pp. 3691-3701.

Abstract

PURPOSE: To evaluate factors affecting corneoscleral profile (CSP) using Anterior Segment Optical Coherence Tomography (AS-OCT) in combination with conventional videokeratoscopy. METHODS: OCT data were collected from 204 subjects of mean age 34.9 years (SD: ±15.2 yrs, range 18 to 65) using the Zeiss Visante AS-OCT and Medmont M300 corneal topographer. Measurements of corneal diameter (CD), corneal sagittal height (CS), iris diameter (ID), corneoscleral junction angle (CSJ) and scleral radius (SR) were extracted from multiple OCT images. Horizontal visible iris diameter (HVID) and vertical palpebral aperture (PA) were measured using a slit lamp graticule. Subject body height was also measured. Associations were then sought between CSP variables and age, height, ethnicity, sex and refractive error data collected. Results: Significant correlations were found between age and ocular topography variables of HVID, PA, CSJ, SR and ID (P<0.0001), while height correlated with HVID, CD and ID, and power vector terms only with vertical plane keratometry, CD and CS. Significant differences were noted between ethnicities with respect to CD (P=0.0046), horizontal and vertical CS (P=0.0068 and P=0.0095), and also horizontal ID (P=0.0010), while the same variables, with the exception of vertical CS, also varied with sex; horizontal CD (P=0.0018), horizontal CS (P=0.0018) and ID (P=0.0012). Age accounted for up to 36% of the variance in CSP variables. Conclusion: Age is the main factor influencing corneoscleral topography; consequently, this should be taken into consideration in contact lens design, in the optimization of surgical procedures involving the cornea and sclera and in IOL selection.

Publication DOI: https://doi.org/10.1167/iovs.13-11657
Divisions: Life & Health Sciences > Optometry
Life & Health Sciences > Ophthalmic Research Group
Life & Health Sciences
Additional Information: Copyright 2013 The Association for Research in Vision and Ophthalmology, Inc
Uncontrolled Keywords: corneoscleral profile,corneal topography,OCT
Full Text Link:
Related URLs: http://www.iovs ... ntent/54/5/3691 (Publisher URL)
Published Date: 2013-04-02
Authors: Hall, Lee
Hunt, Chris
Young, Graeme
Wolffsohn, James ( 0000-0003-4673-8927)

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