Synthesis of S6-(2,4-dinitrophenyl)-6-thioguanosine phosphoramidite and its incorporation into oligoribonucleotides

Zheng, Qinguo, Wang, Yang and Lattmann, Eric (2003). Synthesis of S6-(2,4-dinitrophenyl)-6-thioguanosine phosphoramidite and its incorporation into oligoribonucleotides. Bioorganic and Medicinal Chemistry Letters, 13 (19), pp. 3141-3144.

Abstract

The preparation of N2-phenoxylacetyl-S 6-(2,4-dinitrophenyl)-6-thioguanosine phosphoramidite and its subsequent incorporation into oligoribonucleotides is described. The identity of the oligonucleotides was confirmed by UV spectrophotometry and nucleoside composition analysis. © 2003 Elsevier Ltd. All rights reserved.

Publication DOI: https://doi.org/10.1016/S0960-894X(03)00716-9
Divisions: Life & Health Sciences > Pharmacy
Life & Health Sciences
Uncontrolled Keywords: preparation,N2-phenoxylacetyl-S6-(2,4-dinitrophenyl)-6-thioguanosine phosphoramidite,incorporation,oligoribonucleotides,Biochemistry,Molecular Biology,Organic Chemistry,Drug Discovery,Pharmaceutical Science
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Related URLs: http://www.scop ... tnerID=8YFLogxK (Scopus URL)
Published Date: 2003-10-16
Authors: Zheng, Qinguo
Wang, Yang
Lattmann, Eric

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