The ageing pancreas

Brown, James E. (2012). The ageing pancreas. British Journal of Diabetes and Vascular Disease, 12 (3), pp. 141-145.

Abstract

Type 2 diabetes is historically associated with older adults, and glucose tolerance is known to decline with advancing age. During the course of natural ageing, changes in many peripheral tissues contribute to this deterioration of glucose homeostasis. Included in this process are changes to the structure and function of the pancreatic islets, which undergo deviation in endocrine responses to glycaemic challenge. Current knowledge about the changes seen in the ageing pancreas is reviewed here.

Divisions: ASTON EPrints organisational structure > Schools_of_Study > Life & Health Sciences > Biosciences (LHS)
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Additional Information: Copyright 2012 Elsevier B.V., All rights reserved.
Uncontrolled Keywords: ageing,pancreatic islets ,β-cells
Published Date: 2012-05

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