Kelly, M. Ann, Rees, Simon D., Hydrie, M. Zafar I., Shera, A. Samad, Bellary, Srikanth, O'Hare, J. Paul, Kumar, Sudhesh, Taheri, Shahrad, Basit, Abdul, Barnett, Anthony H., DIAGRAM Consortium and SAT2D consortium (2012). Circadian gene variants and susceptibility to type 2 diabetes:a pilot study. PLoS ONE, 7 (4),
Abstract
Disruption of endogenous circadian rhythms has been shown to increase the risk of developing type 2 diabetes, suggesting that circadian genes might play a role in determining disease susceptibility. We present the results of a pilot study investigating the association between type 2 diabetes and selected single nucleotide polymorphisms (SNPs) in/near nine circadian genes. The variants were chosen based on their previously reported association with prostate cancer, a disease that has been suggested to have a genetic link with type 2 diabetes through a number of shared inherited risk determinants.
| Publication DOI: | https://doi.org/10.1371/journal.pone.0032670 |
|---|---|
| Divisions: | College of Health & Life Sciences > School of Biosciences College of Health & Life Sciences > Chronic and Communicable Conditions College of Health & Life Sciences |
| Additional Information: | © 2012 Kelly et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
| Uncontrolled Keywords: | Agricultural and Biological Sciences(all),Biochemistry, Genetics and Molecular Biology(all),Medicine(all) |
| Last Modified: | 28 Mar 2024 08:11 |
| Date Deposited: | 02 Aug 2012 09:42 |
| Full Text Link: |
http://www.plos ... al.pone.0032670 |
| Related URLs: |
http://www.scop ... tnerID=8YFLogxK
(Scopus URL) |
PURE Output Type: | Article |
| Published Date: | 2012-04-02 |
| Authors: |
Kelly, M. Ann
Rees, Simon D. Hydrie, M. Zafar I. Shera, A. Samad Bellary, Srikanth ( 
0000-0002-5924-5278)
O'Hare, J. Paul Kumar, Sudhesh Taheri, Shahrad Basit, Abdul Barnett, Anthony H. , DIAGRAM Consortium , SAT2D consortium |
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