Zwitterionic and charge-balanced polyampholyte copolymer hydrogels

Campbell, Darren and Tighe, Brian (2008). Zwitterionic and charge-balanced polyampholyte copolymer hydrogels. Advanced Materials Research, 55-57 , pp. 729-732.


Zwitterionic copolymers were synthesised from N,N-dimethyl-N-(2- acryloylethyl)-N-(3-sulfopropyl) ammonium betaine (SPDA) and 2-hydroxyethyl methacrylate (HEMA) produce a series of polyzwitterion hydrogels. For the synthesis of the charge-balanced copolymer hydrogels, two cationic monomers were selected: 2-(diethylamino) ethyl methacrylate (DMAEMA) and 3-(dimethylamino) propyl methacrylamide (DMAPMA), and an anionic monomer; 2-acrylamido-2- methylpropane sulphonic acid (AMPS). Two series of charge-balanced copolymers were synthesized from stoichiometrically equivalent ratios of DMAEMA or DMAPMA and AMPS with HEMA as a termonomer. All synthesized copolymers produced clear and cohesive hydrogels. The zwitterionic and charge-balanced copolymers displayed similar equilibrium water contents together with similar mechanical and surface energy properties. The swelling of the zwitterionic and the charge-balanced copolymers shows some features of antipolyelectrolyte behavior.

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Divisions: Engineering & Applied Sciences > Chemical engineering & applied chemistry
Engineering & Applied Sciences > Biomaterials Research Unit
Uncontrolled Keywords: biomaterial,copolymer,hydrogel,zwitterionic
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Published Date: 2008-08
Authors: Campbell, Darren
Tighe, Brian


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